Approximately 60% of people in the United States experience at least one severe trauma in their lifetime, of which approximately 9% meet full diagnostic criteria for PTSD. Prevalence varies by a population’s traumatic exposure but is estimated to be 12% of patients in primary care. PTSD often goes undiagnosed and untreated, particularly in adult primary care, where patients frequently present with other chief complaints and PTSD is not considered in the differential diagnosis. The debilitating nature of PTSD, coupled with the significant physical, psychological, and social comorbidities and related health care costs, demonstrate the need for improved identification and appropriate intervention by primary care providers.